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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
UAP1_HUMAN
USC-OGP 2-DE database
:
UAP1_HUMAN
UAP1_HUMAN
General information about the entry
View entry in simple text format
Entry name
UAP1_HUMAN
Primary accession number
Q16222
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=UDP-N-acetylhexosamine pyrophosphorylase; AltName: Full=Antigen X; Short=AGX; AltName: Full=Sperm-associated antigen 2; Includes: RecName: Full=UDP-N-acetylgalactosamine pyrophosphorylase; EC=2.7.7.83; AltName: Full=AGX-1; Includes: RecName: Full=UDP-N-acetylglucosamine pyrophosphorylase; EC=2.7.7.23; AltName: Full=AGX-2;.
Gene name
Name=UAP1
Synonyms=SPAG2
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1136
:
pI=6.02; Mw=63196
SPOT OGP-1149
:
pI=6.17; Mw=55186
Cross-references
UniProtKB/Swiss-Prot
Q16222; UAP1_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
UAP1_HUMAN
Primary accession number
Q16222
Secondary accession number(s)
B2R6R8 Q5VTA9 Q5VTB0 Q5VTB1 Q96GM2
Sequence was last modified on
July 5, 2005 (version 3)
Annotations were last modified on
March 15, 2017 (version 170)
Name and origin of the protein
Description
RecName: Full=UDP-N-acetylhexosamine pyrophosphorylase; AltName: Full=Antigen X; Short=AGX; AltName: Full=Sperm-associated antigen 2; Includes: RecName: Full=UDP-N-acetylgalactosamine pyrophosphorylase; EC=2.7.7.83; AltName: Full=AGX-1; Includes: RecName: Full=UDP-N-acetylglucosamine pyrophosphorylase; EC=2.7.7.23; AltName: Full=AGX-2;
Gene name
Name=UAP1
Synonyms=SPAG2
Encoded on
Name=UAP1; Synonyms=SPAG2
Keywords
3D-structure
;
Alternative splicing
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Nucleotidyltransferase
;
Polymorphism
;
Reference proteome
;
Transferase
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
S73498; AAB31210.2
; -; mRNA
EMBL
AB011004; BAA31202.1
; -; mRNA
EMBL
AK312685; BAG35565.1
; -; mRNA
EMBL
AL596325; CAH72978.1
; -; Genomic_DNA
EMBL
AL596325; CAH72979.1
; -; Genomic_DNA
EMBL
AL596325; CAH72980.1
; -; Genomic_DNA
EMBL
CH471067; EAW90710.1
; -; Genomic_DNA
EMBL
BC009377; AAH09377.1
; -; mRNA
CCDS
CCDS1240.1; -. [Q16222-2]
; .
CCDS
CCDS81393.1; -. [Q16222-1]
; .
CCDS
CCDS81394.1; -. [Q16222-3]
; .
RefSeq
NP_001311042.1; NM_001324113.1. [Q16222-2]
; .
RefSeq
NP_001311043.1; NM_001324114.1. [Q16222-2]
; .
RefSeq
NP_001311044.1; NM_001324115.1. [Q16222-2]
; .
RefSeq
NP_001311045.1; NM_001324116.1. [Q16222-1]
; .
RefSeq
NP_001311046.1; NM_001324117.1. [Q16222-3]
; .
RefSeq
NP_003106.3; NM_003115.4. [Q16222-2]
; .
RefSeq
XP_011508215.1; XM_011509913.2. [Q16222-1]
; .
RefSeq
XP_011508216.1; XM_011509914.2. [Q16222-1]
; .
UniGene
Hs.492859; -
; .
PDB
1JV1; X-ray
; 1.90 A; A/B=1-522
PDB
1JV3; X-ray
; 2.20 A; A/B=1-522
PDB
1JVD; X-ray
; 2.40 A; A/B=1-522
PDB
1JVG; X-ray
; 2.30 A; A/B=1-522
PDBsum
1JV1; -
; .
PDBsum
1JV3; -
; .
PDBsum
1JVD; -
; .
PDBsum
1JVG; -
; .
DisProt
DP00363; -
; .
ProteinModelPortal
Q16222; -
; .
SMR
Q16222; -
; .
BioGrid
112557; 20
; .
IntAct
Q16222; 7
; .
STRING
9606.ENSP00000356903; -
; .
DrugBank
DB02196; Uridine-Diphosphate-N-Acetylgalactosamine
; .
DrugBank
DB03397; Uridine-Diphosphate-N-Acetylglucosamine
; .
iPTMnet
Q16222; -
; .
PhosphoSitePlus
Q16222; -
; .
BioMuta
UAP1; -
; .
DMDM
68846235; -
; .
REPRODUCTION-2DPAGE
IPI00217816; -
; .
EPD
Q16222; -
; .
MaxQB
Q16222; -
; .
PaxDb
Q16222; -
; .
PeptideAtlas
Q16222; -
; .
PRIDE
Q16222; -
; .
Ensembl
ENST00000271469; ENSP00000271469
; ENSG00000117143. [Q16222-1]; .
Ensembl
ENST00000367924; ENSP00000356901
; ENSG00000117143. [Q16222-3]; .
Ensembl
ENST00000367925; ENSP00000356902
; ENSG00000117143. [Q16222-1]; .
Ensembl
ENST00000367926; ENSP00000356903
; ENSG00000117143. [Q16222-2]; .
GeneID
6675; -
; .
KEGG
hsa:6675; -
; .
UCSC
uc001gce.5; human. [Q16222-1]
; .
CTD
6675; -
; .
DisGeNET
6675; -
; .
GeneCards
UAP1; -
; .
H-InvDB
HIX0001264; -
; .
HGNC
HGNC:12457; UAP1
; .
HPA
HPA014659; -
; .
MIM
602862; gene
; .
neXtProt
NX_Q16222; -
; .
OpenTargets
ENSG00000117143; -
; .
PharmGKB
PA37107; -
; .
eggNOG
KOG2388; Eukaryota
; .
eggNOG
COG4284; LUCA
; .
GeneTree
ENSGT00390000010072; -
; .
HOGENOM
HOG000186273; -
; .
HOVERGEN
HBG018024; -
; .
InParanoid
Q16222; -
; .
KO
K00972; -
; .
OMA
YAGENLV; -
; .
OrthoDB
EOG091G05FO; -
; .
PhylomeDB
Q16222; -
; .
TreeFam
TF300611; -
; .
BRENDA
2.7.7.83; 2681
; .
Reactome
R-HSA-446210; Synthesis of UDP-N-acetyl-glucosamine
; .
SABIO-RK
Q16222; -
; .
UniPathway
UPA00113; UER00533
; .
ChiTaRS
UAP1; human
; .
EvolutionaryTrace
Q16222; -
; .
GeneWiki
UAP1; -
; .
GenomeRNAi
6675; -
; .
PRO
PR:Q16222; -
; .
Proteomes
UP000005640; Chromosome 1
; .
Bgee
ENSG00000117143; -
; .
CleanEx
HS_UAP1; -
; .
ExpressionAtlas
Q16222; baseline and differential
; .
Genevisible
Q16222; HS
; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0005654; C:nucleoplasm
; IDA:HPA; .
GO
GO:0005886; C:plasma membrane
; IDA:HPA; .
GO
GO:0030246; F:carbohydrate binding
; IEA:Ensembl; .
GO
GO:0042802; F:identical protein binding
; IPI:IntAct; .
GO
GO:0003977; F:UDP-N-acetylglucosamine diphosphorylase activity
; IBA:GO_Central; .
GO
GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process
; IBA:GO_Central; .
Gene3D
3.90.550.10; -
; 1; .
InterPro
IPR029044; Nucleotide-diphossugar_trans
; .
InterPro
IPR002618; UDPGP_fam
; .
Pfam
PF01704; UDPGP
; 1; .
SUPFAM
SSF53448; SSF53448
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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